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##  91 results 

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### 2025

Timothy M Kistner, Beckey Trinh, Karl Mfeketo, Gerrit van Hall, Bente K Pedersen, Daniel E Lieberman, and Helga Ellingsgaard. 2025. “[Myokine IL-6 Activity Enhances Post-Exercise Fatty Acid Accumulation in Skeletal Muscle But Does Not Affect Glycogen Resynthesis.](/publication/myokine-il-6-activity-enhances-post-exercise-fatty-acid-accumulation-skeletal-muscle)”. Molecular Metabolism, 103, Pp. 102283. doi:10.1016/j.molmet.2025.102283



 

 

Timothy M Kistner, Beckey Trinh, Karl Mfeketo, Gerrit van Hall, Bente K Pedersen, Daniel E Lieberman, and Helga Ellingsgaard. 2025. “[Myokine IL-6 Activity Enhances Post-Exercise Fatty Acid Accumulation in Skeletal Muscle But Does Not Affect Glycogen Resynthesis.](/publication/myokine-il-6-activity-enhances-post-exercise-fatty-acid-accumulation-skeletal-muscle)”. Molecular Metabolism, 103, Pp. 102283. doi:10.1016/j.molmet.2025.102283



 

 

 

- add\_circle\_outline do\_not\_disturb\_on Abstract
 
BACKGROUND/PURPOSE: During exercise, myokine interleukin 6 (IL-6) plays a variety of metabolic roles including acting as a muscular energy sensor and liberating somatic energy stores. While the effects of IL-6 are relatively well-defined during exercise...



 

 

 

Christopher MacDonald, Mia Bennekou, Julie Midtgaard, Henning Langberg, and Daniel E Lieberman. 2025. “[Clarifying the Real Challenge: Adherence, Not Efficacy, Is the Barrier to Exercise As Medicine.](/publication/clarifying-real-challenge-adherence-not-efficacy-barrier-exercise-medicine)”. British Journal of Sports Medicine. doi:10.1136/bjsports-2025-110988



 

 

Christopher MacDonald, Mia Bennekou, Julie Midtgaard, Henning Langberg, and Daniel E Lieberman. 2025. “[Clarifying the Real Challenge: Adherence, Not Efficacy, Is the Barrier to Exercise As Medicine.](/publication/clarifying-real-challenge-adherence-not-efficacy-barrier-exercise-medicine)”. British Journal of Sports Medicine. doi:10.1136/bjsports-2025-110988



 

 

 

 

Alexandra R Harris, Andrew K Yegian, Benjamin E Sibson, Aimable Uwimana, Jean-Baptiste Niyibizi, Denis Regnier, Robert M Ojiambo, Asuman Nuhu, Alec Thomas, Laszlo Kocsis, Torsten Vennemann, Aaron L Baggish, and Daniel E Lieberman. 2025. “[Comparing Physical Activity Levels and Metabolic Quotients to Quantify the Physical Activity Transition in Rwanda.](/publication/comparing-physical-activity-levels-and-metabolic-quotients-quantify-physical-activity)”. American Journal of Human Biology : The Official Journal of the Human Biology Council, 37, 9, Pp. e70142. doi:10.1002/ajhb.70142



 

 

Alexandra R Harris, Andrew K Yegian, Benjamin E Sibson, Aimable Uwimana, Jean-Baptiste Niyibizi, Denis Regnier, Robert M Ojiambo, Asuman Nuhu, Alec Thomas, Laszlo Kocsis, Torsten Vennemann, Aaron L Baggish, and Daniel E Lieberman. 2025. “[Comparing Physical Activity Levels and Metabolic Quotients to Quantify the Physical Activity Transition in Rwanda.](/publication/comparing-physical-activity-levels-and-metabolic-quotients-quantify-physical-activity)”. American Journal of Human Biology : The Official Journal of the Human Biology Council, 37, 9, Pp. e70142. doi:10.1002/ajhb.70142



 

 

 

- add\_circle\_outline do\_not\_disturb\_on Abstract
 
OBJECTIVES: Although humans used to be physically active hunter-gatherers and subsistence farmers, there has been a recent and ongoing global physical activity transition as billions of people adopt industrial lifestyles primarily in urban areas. In order...



 

 

 

Benjamin E Sibson, Andrew K Yegian, Ali Yawar, and Daniel E Lieberman. 2025. “[Effects of Back Muscle Fatigue and Modified Trunk Inertia on Lumbar Kinematics, Kinetics and Muscle Activity During Walking.](/publication/effects-back-muscle-fatigue-and-modified-trunk-inertia-lumbar-kinematics-kinetics-and)”. The Journal of Experimental Biology, 228, 9. doi:10.1242/jeb.250479



 

 

Benjamin E Sibson, Andrew K Yegian, Ali Yawar, and Daniel E Lieberman. 2025. “[Effects of Back Muscle Fatigue and Modified Trunk Inertia on Lumbar Kinematics, Kinetics and Muscle Activity During Walking.](/publication/effects-back-muscle-fatigue-and-modified-trunk-inertia-lumbar-kinematics-kinetics-and)”. The Journal of Experimental Biology, 228, 9. doi:10.1242/jeb.250479



 

 

 

- add\_circle\_outline do\_not\_disturb\_on Abstract
 
Back endurance is a strong predictor of back pain, but the mechanisms underlying this relationship are not clear. Fatigue reduces muscles' force-generating capacity, so greater fatigability may increase lumbar motion and loading and trunk muscle co...



 

 

 

Lauren M Baker, Fabian C Weigend, Krithika Swaminathan, Daekyum Kim, Andrew Chin, Daniel E Lieberman, and Conor J Walsh. 2025. “[Estimating Braking and Propulsion Forces During Overground Running in and Out of the Lab.](/publication/estimating-braking-and-propulsion-forces-during-overground-running-and-out-lab)”. PloS One, 20, 9, Pp. e0330042. doi:10.1371/journal.pone.0330042



 

 

Lauren M Baker, Fabian C Weigend, Krithika Swaminathan, Daekyum Kim, Andrew Chin, Daniel E Lieberman, and Conor J Walsh. 2025. “[Estimating Braking and Propulsion Forces During Overground Running in and Out of the Lab.](/publication/estimating-braking-and-propulsion-forces-during-overground-running-and-out-lab)”. PloS One, 20, 9, Pp. e0330042. doi:10.1371/journal.pone.0330042



 

 

 

- add\_circle\_outline do\_not\_disturb\_on Abstract
 
Accurately estimating kinetic metrics, such as braking and propulsion forces, in real-world running environments enhances our understanding of performance, fatigue, and injury. Wearable inertial measurement units (IMUs) offer a potential solution to...



 

 

 

 



### 2024

Christopher Scott MacDonald, Mia Aagaard Bennekou, Sabrina Mai Nielsen, Anders Ellekær Junker, Tor Biering-Sørensen, Henning Langberg, Robin Christensen, Daniel E Lieberman, Claus Zachariae, and Jannik Langtved Pallisgaard. 2024. “[Evolutionary Mismatch and Lifestyle-Related Diseases: A Study of a 6-Month Intensive Lifestyle Intervention.](/publication/evolutionary-mismatch-and-lifestyle-related-diseases-study-6-month-intensive-lifestyle)”. Scandinavian Journal of Medicine &amp; Science in Sports, 34, 12, Pp. e14770. doi:10.1111/sms.14770



 

 

Christopher Scott MacDonald, Mia Aagaard Bennekou, Sabrina Mai Nielsen, Anders Ellekær Junker, Tor Biering-Sørensen, Henning Langberg, Robin Christensen, Daniel E Lieberman, Claus Zachariae, and Jannik Langtved Pallisgaard. 2024. “[Evolutionary Mismatch and Lifestyle-Related Diseases: A Study of a 6-Month Intensive Lifestyle Intervention.](/publication/evolutionary-mismatch-and-lifestyle-related-diseases-study-6-month-intensive-lifestyle)”. Scandinavian Journal of Medicine &amp; Science in Sports, 34, 12, Pp. e14770. doi:10.1111/sms.14770



 

 

 

- add\_circle\_outline do\_not\_disturb\_on Abstract
 
Chronic medical conditions caused by the inadequate adaptation of the body to modern lifestyles, such as physical inactivity and unhealthy diets, are on the rise. This study assessed whether a comprehensive lifestyle intervention, including high volumes...



 

 

 

Andrew K Yegian, Steven B Heymsfield, Eric R Castillo, Manfred J Müller, Leanne M Redman, and Daniel E Lieberman. 2024. “[Metabolic Scaling, Energy Allocation Tradeoffs, and the Evolution of Humans’ Unique Metabolism.](/publication/metabolic-scaling-energy-allocation-tradeoffs-and-evolution-humans-unique-metabolism)”. Proceedings of the National Academy of Sciences of the United States of America, 121, 48, Pp. e2409674121. doi:10.1073/pnas.2409674121



 

 

Andrew K Yegian, Steven B Heymsfield, Eric R Castillo, Manfred J Müller, Leanne M Redman, and Daniel E Lieberman. 2024. “[Metabolic Scaling, Energy Allocation Tradeoffs, and the Evolution of Humans’ Unique Metabolism.](/publication/metabolic-scaling-energy-allocation-tradeoffs-and-evolution-humans-unique-metabolism)”. Proceedings of the National Academy of Sciences of the United States of America, 121, 48, Pp. e2409674121. doi:10.1073/pnas.2409674121



 

 

 

- add\_circle\_outline do\_not\_disturb\_on Abstract
 
All organisms use limited energy to grow, survive, and reproduce, necessitating energy allocation tradeoffs, but there is debate over how selection impacted metabolic budgets and tradeoffs in primates, including humans. Here, we develop a method to...



 

 

 

Timothy M Kistner, Anna Tavormina, and Daniel E Lieberman. 2024. “[Myokine Secretion During Moderate-Intensity Physical Activity: Dose-Response of Interleukin 6 to Walking Duration.](/publication/myokine-secretion-during-moderate-intensity-physical-activity-dose-response-interleukin)”. American Journal of Human Biology : The Official Journal of the Human Biology Council, 36, 10, Pp. e24131. doi:10.1002/ajhb.24131



 

 

Timothy M Kistner, Anna Tavormina, and Daniel E Lieberman. 2024. “[Myokine Secretion During Moderate-Intensity Physical Activity: Dose-Response of Interleukin 6 to Walking Duration.](/publication/myokine-secretion-during-moderate-intensity-physical-activity-dose-response-interleukin)”. American Journal of Human Biology : The Official Journal of the Human Biology Council, 36, 10, Pp. e24131. doi:10.1002/ajhb.24131



 

 

 

- add\_circle\_outline do\_not\_disturb\_on Abstract
 
During vigorous physical activity, contracting muscles secrete a variety of immunomodulatory and metabolic factors called myokines that perform a variety of functions. Foremost among these is interleukin 6 (IL-6), which increases fatty acid mobilization...



 

 

 

Ali Yawar and Daniel E Lieberman. 2024. “[Effects of Shoe Heel Height on Ankle Dynamics in Running.](/publication/effects-shoe-heel-height-ankle-dynamics-running)”. Scientific Reports, 14, 1, Pp. 17959. doi:10.1038/s41598-024-68519-z



 

 

Ali Yawar and Daniel E Lieberman. 2024. “[Effects of Shoe Heel Height on Ankle Dynamics in Running.](/publication/effects-shoe-heel-height-ankle-dynamics-running)”. Scientific Reports, 14, 1, Pp. 17959. doi:10.1038/s41598-024-68519-z



 

 

 

- add\_circle\_outline do\_not\_disturb\_on Abstract
 
Shoes affect the evolved biomechanics of the foot, potentially affecting running kinematics and kinetics that can in turn influence injury and performance. An important feature of conventional running shoes is heel height, whose effects on foot and ankle...



 

 

 

Lauren M Baker, Ali Yawar, Daniel E Lieberman, and Conor J Walsh. 2024. “[Predicting Overstriding With Wearable IMUs During Treadmill and Overground Running.](/publication/predicting-overstriding-wearable-imus-during-treadmill-and-overground-running)”. Scientific Reports, 14, 1, Pp. 6347. doi:10.1038/s41598-024-56888-4



 

 

Lauren M Baker, Ali Yawar, Daniel E Lieberman, and Conor J Walsh. 2024. “[Predicting Overstriding With Wearable IMUs During Treadmill and Overground Running.](/publication/predicting-overstriding-wearable-imus-during-treadmill-and-overground-running)”. Scientific Reports, 14, 1, Pp. 6347. doi:10.1038/s41598-024-56888-4



 

 

 

- add\_circle\_outline do\_not\_disturb\_on Abstract
 
Running injuries are prevalent, but their exact mechanisms remain unknown largely due to limited real-world biomechanical analysis. Reducing overstriding, the horizontal distance that the foot lands ahead of the body, may be relevant to reducing injury...



 

 

 

Benjamin E Sibson, Alexandra R Harris, Andrew K Yegian, Aimable Uwimana, Assuman Nuhu, Alec Thomas, Dennis E Anderson, Robert M Ojiambo, and Daniel E Lieberman. 2024. “[Associations of Back Muscle Endurance With Occupational Back Muscle Activity and Spinal Loading Among Subsistence Farmers and Office Workers in Rwanda.](/publication/associations-back-muscle-endurance-occupational-back-muscle-activity-and-spinal-loading)”. PloS One, 19, 11, Pp. e0309658. doi:10.1371/journal.pone.0309658



 

 

Benjamin E Sibson, Alexandra R Harris, Andrew K Yegian, Aimable Uwimana, Assuman Nuhu, Alec Thomas, Dennis E Anderson, Robert M Ojiambo, and Daniel E Lieberman. 2024. “[Associations of Back Muscle Endurance With Occupational Back Muscle Activity and Spinal Loading Among Subsistence Farmers and Office Workers in Rwanda.](/publication/associations-back-muscle-endurance-occupational-back-muscle-activity-and-spinal-loading)”. PloS One, 19, 11, Pp. e0309658. doi:10.1371/journal.pone.0309658



 

 

 

- add\_circle\_outline do\_not\_disturb\_on Abstract
 
Over the course of the physical activity transition, machines have largely replaced skeletal muscle as the source of work for locomotion and other forms of occupational physical activity in industrial environments. To better characterize this transition...



 

 

 

Benjamin E Sibson, Jacob J Banks, Ali Yawar, Andrew K Yegian, Dennis E Anderson, and Daniel E Lieberman. 2024. “[Using Inertial Measurement Units to Estimate Spine Joint Kinematics and Kinetics During Walking and Running.](/publication/using-inertial-measurement-units-estimate-spine-joint-kinematics-and-kinetics-during)”. Scientific Reports, 14, 1, Pp. 234. doi:10.1038/s41598-023-50652-w



 

 

Benjamin E Sibson, Jacob J Banks, Ali Yawar, Andrew K Yegian, Dennis E Anderson, and Daniel E Lieberman. 2024. “[Using Inertial Measurement Units to Estimate Spine Joint Kinematics and Kinetics During Walking and Running.](/publication/using-inertial-measurement-units-estimate-spine-joint-kinematics-and-kinetics-during)”. Scientific Reports, 14, 1, Pp. 234. doi:10.1038/s41598-023-50652-w



 

 

 

- add\_circle\_outline do\_not\_disturb\_on Abstract
 
Optical motion capture (OMC) is considered the best available method for measuring spine kinematics, yet inertial measurement units (IMU) have the potential to collect data outside the laboratory. When combined with musculoskeletal modeling, IMU...



 

 

 

 



 

 

 

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